best flea medicine for cats

What Is The Most Effective And Best Flea Medicine For Cats?


It is not a pretty sight watching a cat scratching because of fleas and it can be a shock to realize that the problem is worse than it first seemed.

​Some links may be affiliate links. We may get paid if you buy something or take an action after clicking one of these links.

What Is The Best Flea Medicine For Cats?

​Cat F​lea Drops

For fast acting results ​​​​and easy and convenient application you hands down can’t beat the cat flea drops that are applied once per month.  

The drops really are the gold standard. They are easy to apply and work efficiently for up to 30 days.

Cat Flea Drops - How Do They Work?

The topical drops ​last one month, although some manufacturers will say that the protection does last a bit longer than one month. That does take some experimenting.

We have always found that it is pretty well spot on a month and then more drops need to be applied.

The applicator makes these drops easy to apply. It is just a matter of snapping off the top or sometimes cutting the top, parting kitties fur between the shoulder blades and squeezing the applicator gently to distribute the product.

The cat cannot reach around to lick the product, however, if possible, just keep kitty quiet for a minute or two until the product dries. If your kitty is like ​many and has already headed for the hills as soon as the application is done, well there's nothing you can do about that.

The product does fortunately dry very quickly.

best flea medicine for cats

This is actually really easy to do and then, that's it for a month.

​​This type of flea medicine is popular because it works, it is easy to apply and the once a month application is appealing.

There are always exceptions and sometimes a cat may have an allergy to a product, so keep this in mind when using a new product and observe ​your cat to make sure all is okay.

If you suspect there is an allergy a visit to the vet for medical advice will be necessary. ​

​Cat Flea Drops Reviews

Frontline Plus flea medicine

Frontline Plus For Cats

​​Frontline is suitable for cats and also kittens over eight weeks old and weighing more than 1.5 lbs.  

This product kills fleas, flea eggs & larvae. ticks and chewing lice. It also kills the ticks that may transmit Lyme disease.

The two ingredients that work so efficiently are fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae.

​The information here describes in detail the instructions for use and common FAQ ​in relation to this product.  When opening the webpage, scroll just past the i​mages to find ​- Description, Ingredients, Instructions and FAQ. This is detailed, practical information. There ​is also a Question and Answer section which further highlights information you may need and asks the sort of questions you want to ask

We have used this product for years and it ​​reli​ably performs well. The only exception is forgetting to reapply and that is human problem.

As a dosing reminder, Frontline comes with six small stickers that can be attached to the calendar on a particular day of the month as a reminder to dose the cat.

If you would like more information about the chemicals used and exactly how they work this is a detailed article from a veterinary perspective.

Frontline Plus flea medicine
5 of 5 Stars
Advantage Flea Control for Cats

Advantage Flea Control for Cats

This treatment is also applied topically in the same manner as Frontline.

It works successfully on indoor and outdoor cats. It is applied once a month which is the same protocol as other treatment of this type. Indoor cats can still get fleas as the fleas come inside the house.

It stops fleas feeding within minutes and kills adult fleas and larvae. This product works on contact so fleas do not have to actually bite resulting in fewer flea bites on the cat.

It is water resistant but don't apply it if the cat is wet.

Once possible side effect and I have seen this recorded is loss of hair at the site of application. This does happen occasionally and is reported as usually being a single occurrence with the hair regrowing. 

The treatment shown in the image is for cats over 9 lb as you can tell by the purple tag in the top right of the packaging.

Different treatments are also available for cats of different weights as shown here​ for kittens 2-5 lbs, cats 5-9 lbs and cats over 9lbs.

In addition these treatments can be purchased in 2 doses, 4 doses and 6 doses.  That covers all options and gives you the choice to try a 2 dose pack if this is a product you haven't tried before and want to give it a go.

There is specific information here about the product, how to apply it and use it efficiently.

4.5 of 5 Stars
Sentry Fiproguard Flea Drops for cats

Sentry Fiproguard Plus For Cats

This is a six dose product.  The active ingredients are the same as Frontline Plus.

​The solution is waterproof and suitable for cats over 8 weeks of age or weighing 1.5 pounds or more. Weigh your cat before purchasing if you are not sure of the cat's weight.

Do not treat with more than one pesticide product at a time, so don't use this product at the same time as using a flea collar.​

This treatment can be used on pregnant and nursing cats.

4.5 of 5 Stars

How To Apply Cat Flea Drops - Video

This is a particularly good video showing how to apply Frontline Plus.

It is being applied to a dog however the same method applies to a cat.  

This video shows very clearly how to part the fur and how to place the product from the pipette onto the skin.  ​Do this as shown because the formula is stored in the oil glands of the cat's skin.

It is a very simple procedure, however you know your kitty the best, so it may be a two person job, as shown with the dog in the video, to make sure it is applied correctly.


​​Why Use Cat Flea Tablets?

​Flea medicine can also refer to medication that is taken orally as tablets. Instead of applying drops, using a flea collar or flea powder or  flea spray this medication is in tablet form. Normally it is a one off treatment that effectively treats a f​lea infestation.

The tablets referred to below both contain a product called nitenpyram. There is more information about nitenpyram and how it works here.

How To Check Your Cat For Fleas

The cat can have a flea infestation and may not necessarily be scratching madly all the time. Although scratching is the most obvious sign of fleas, it is essential to actually check for fleas on a regular basis.

This video shows how easy it is to do just that.

Our Recommendation is...

​Frontline Plus For Cats


​​​For the gold standard in cat flea drops we recommend w​​​​e recommend Fro​​​​​​​​​ntline Plus.

This treatment  kills adult fleas and ticks  plus flea eggs, larvae and chewing lice for up to three months. This is a veterinarian recommended treatment.

Overall rating :  5 / 5

​Here ​is ​​more information about ​alternative flea treatments for cats. If you are looking for a long lasting option, then a flea collar will work well. Some cats are not so keen on collars.  ​The drops are also convenient and efficient.

flea collars for cats

​A Flea Collar For Cats Is An Effective Option

​Put on once and forget for 8 months.  It has got appeal.

cat having a flea shampoo

​Shampoo For Cat Fleas

​A solution when you need instant results.

flea spray for cats

​Cat Flea Spray Is Fast Acting

​Cat flea spray is​ useful when an infestation is ​discovered and you​ need to take action immediately for the cat’s comfort. 

Why Buy From Chewy?

​Chewy has an outstanding ​track record for customer service and super fast delivery. The questions in Chewy's FAQ  are ones ​we all want to ask and that are helpful, for example:

How long does it take to get my order?
How much is shipping?
What do I do if I need to return something?
How does Chewy get authorization from my vet for prescription items?

Click here to read the FAQ from Chewy

The best flea medicine for cats

About the Author Rebecca Parker

Hello! I am Rebecca Parker, the content editor of this site. This is my kitty cat in his heyday. He now has diabetes which means twice daily injections and much to his dismay, no more snacking in between meals. This gorgeous and very loved kitty is sadly now deceased, old age caught up with him.