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What Is The Most Effective And Best Flea Medicine For Cats?

The best flea medicine could be talking about cat flea drops that are applied to the skin or a cat flea pill or tablet. This article is primarily about cat flea drops. If you are looking for a cat flea pill or tablet this is a link to the article that reviews cat flea tablets and provides more information.

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The Best Flea Medicine For Cats

Cat Flea Drops

For fast acting results and easy and convenient application you hands down can’t beat the cat flea drops that are applied once per month.  The drops really are the gold standard. They are easy to apply and work efficiently for up to 30 days.

Cat Flea Drops – How Do They Work?

The topical drops last one month, although some manufacturers will say that the protection does last a bit longer than one month.


We have always found that it is pretty well spot on a month and then more drops need to be applied.
The applicator makes these drops easy to apply.


It is just a matter of snapping off the top or sometimes cutting the top, parting kitties fur between the shoulder blades and squeezing the applicator gently to distribute the product.

You will become a pro at doing this. The cat cannot reach around to lick the product, however, if possible, just keep kitty quiet for a minute or two until the product dries.

If your kitty is like many and has already headed for the hills as soon as the application is done, well there’s nothing you can do about that. The product does fortunately dry very quickly.

best flea medicine for cats
This is actually really easy to do and then, that’s it for a month.

This is the best flea medicine for cats, it is popular because it Works, it is Easy to Apply and the once a month application is appealing.

There are always exceptions and sometimes a cat may have an allergy to a product, so keep this in mind when using a new product. Observe your cat to make sure all is okay.

If you suspect there is an allergy a visit to the vet for medical advice will be necessary.

1. Frontline Plus For Cats – First Choice
2. Advantage Flea Control For Cats – Very Similar to Frontline
3. Sentry Fiproguard Plus For CatsEconomical

Best Flea Medicine For Cats Reviews

1. Frontline Plus For Cats

Frontline Plus Flea and Tick Treatment for Cats

Frontline is suitable for cats and also kittens over eight weeks old and weighing more than 1.5 lbs.  

This product kills fleas, flea eggs & larvae, ticks and chewing lice. It also kills the ticks that may transmit Lyme disease.

The two ingredients that work so efficiently are fipronil and (S)-methoprene – one to kill adult fleas and ticks and the second to kill flea eggs and larvae. We have used this product for years and it reliably performs well. The only exception is forgetting to reapply and that is human problem.

As a dosing reminder, Frontline comes with six small stickers that can be attached to the calendar on a particular day of the month as a reminder to dose the cat. Now if someone would remind me to use the reminder stickers!

If you would like more information about the chemicals used and exactly how they work this is a detailed article from a veterinary perspective.

Put a cat flea collar on once and forget for 8 months.  It has got appeal.


2. Advantage Flea Control for Cats

Advantage II 6-Dose Large Cat Flea Prevention, Flea Prevention for Cats, Over 9 Pounds

This treatment is also applied topically in the same manner as Frontline. Both products are extremely popular. You may need to set up your own testing regime to see what works best for your cat.

It works successfully on indoor and outdoor cats. It is applied once a month which is the same protocol as other treatments of this type.

Indoor cats can still get fleas as the fleas come inside the house. This product stops fleas feeding within minutes and kills adult fleas and larvae. This product works on contact so fleas do not have to actually bite resulting in fewer flea bites on the cat.

It is water resistant but don’t apply it if the cat is wet.

Once possible side effect and I have seen this recorded is loss of hair at the site of application. This does happen occasionally and is reported as usually being a single occurrence with the hair regrowing. 

The treatment shown in the image is for cats over 9 lb as you can tell by the purple tag in the top right of the packaging.

Different treatments are also available for cats of different weights as shown here for kittens 2-5 lbs, cats 5-9 lbs and cats over 9lbs.In addition these treatments can be purchased in 2 doses, 4 doses and 6 doses.  That covers all options and gives you the choice to try a 2 dose pack if this is a product you haven’t tried before and want to give it a go.

3. Sentry Fiproguard Plus For Cats

SENTRY Fiproguard Plus Flea and Tick Topical for Cats, 1.5 lbs and Over, 6 Month Supply

This is a six dose product.  The active ingredients are the same as Frontline Plus.

The solution is waterproof and suitable for cats over 8 weeks of age or weighing 1.5 pounds or more. Weigh your cat before purchasing if you are not sure of the cat’s weight.

Do not treat with more than one pesticide product at a time, so don’t use this product at the same time as using a flea collar.

This treatment can be used on pregnant and nursing cats.

Flea shampoo is a good solid solution when you need instant results.

Our Recommendation is…

#1. Frontline Plus For Cats

For the gold standard in cat flea drops we recommend we recommend Frontline Plus.

This treatment  kills adult fleas and ticks  plus flea eggs, larvae and chewing lice for up to three months. This is a veterinarian recommended treatment.

Cat flea spray is useful when a flea infestation is discovered and you need to take action immediately for the cat’s comfort. 

How To Apply Cat Flea Drops  

This is a particularly good video showing how to apply Frontline Plus. It is being applied to a dog however the same method applies to a cat.  

This video shows very clearly how to part the fur and how to place the product from the pipette onto the skin.  Do this as shown because the formula is stored in the oil glands of the cat’s skin.

It is a very simple procedure, however you know your kitty the best, so it may be a two person job, to make sure it is applied correctly.

Why Use Cat Flea Tablets?

Flea medicine can also refer to flea medication that is taken orally as tablets. Instead of applying drops, using a flea collar or flea powder or  flea spray this medication is in tablet form. Normally it is a one off treatment that effectively treats a flea infestation.

How To Check Your Cat For Fleas

The cat can have a flea infestation and may not necessarily be scratching madly all the time. Although scratching is the most obvious sign of fleas, it is essential to actually check for fleas on a regular basis. This video shows how easy it is to do just that.

1. Frontline Plus For Cats – First Choice
2. Advantage Flea Control For Cats – Very Similar to Frontline
3. Sentry Fiproguard Plus For CatsEconomical
best flea medicine
What’s the date dear? I think our next dose must be coming up soon!

cat flea medicine

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